Sildenafil citrate,171599-83-0 |
In clinical trials, the most common adverse effects of Sildenafil citrate use included headache, flushing, dyspepsia, nasal congestion and impaired vision, including photophobia and blurred vision.Some Sildenafil citrate users have complained of seeing everything tinted blue (cyanopsia).Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that Sildenafil citrate could lead to vision impairment in rare cases.and a number of studies have linked Sildenafil citrate use with nonarteritic anterior ischemic optic neuropathy.
Rare but serious adverse effects found through postmarketing surveillance include priapism, severe hypotension, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss.As a result of these postmarketing reports, in October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including Sildenafil citrate, required a more prominent warning of the potential risk of sudden hearing loss.
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