2013年9月30日星期一

2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide

2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide (INN) is a common local anesthetic and antiarrhythmic drug. 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery.
1.How should this medicine be used?
2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide viscous comes as a thick liquid and should be shaken well before using. 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide viscous usually is used as needed but not more frequently than every 3 hours, with a maximum of 8 doses in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
For a sore or irritated mouth, the dose should be placed in the mouth, swished around until the pain goes away, and spit out.
For a sore throat, the dose should be gargled and then may be swallowed. To avoid or decrease side effects, use the minimum amount of drug needed to relieve your pain.
Because 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide viscous decreases the feeling in your mouth and/or throat, it may affect your ability to swallow. Avoid eating for at least 1 hour after you have used this drug. You should also avoid chewing gum while using this medication.
2.Missed dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
3.Side effect
Adverse drug reactions (ADRs) are rare when 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide is used as a local anesthetic and is administered correctly. Most ADRs associated with 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide for anesthesia relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, and allergic reactions only rarely occur.
Systemic exposure to excessive quantities of 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide mainly result in central nervous system (CNS) and cardiovascular effects – CNS effects usually occur at lower blood plasma concentrations and additional cardiovascular effects present at higher concentrations, though cardiovascular collapse may also occur with low concentrations. CNS effects may include CNS excitation (nervousness, tingling around the mouth (also known as circumoral paraesthesia), tinnitus, tremor, dizziness, blurred vision, seizures) followed by depression, and with increasingly heavier exposure: drowsiness, loss of consciousness, respiratory depression and apnoea. Cardiovascular effects include hypotension, bradycardia, arrhythmias, and/or cardiac arrest – some of which may be due to hypoxemia secondary to respiratory depression.

没有评论:

发表评论