Information of niclosamide

　　Niclosamide is an anthelmintic, prescribed for worm infections (fish tapeworm, dwarf tapeworm, and beef tapeworm infections). It is also used as a piscicide (poisonous to fish).  It works by killing tapeworms on contact.

niclosamide

　　
Name:Niclosamide

EINECS:200-056-8

Molecular Formula:C13H8Cl2N2O4

CAS Registry Number:50-65-7

Appearance:white to yellowish odourless crystalline powder

Molecular Weight:327.11962

Density:1.616g/cm3

Boiling Point:424.5 °C at 760 mmHg

Melting Point:225-230 DEG C

Flash Point:210.5 °C

Refractive index:1.709

Solubility:Insoluble Appearance:white to yellowish odourless crystalline powderTransport Information:UN 3077

application: Niclosamide is a lampricide and molluscicide. It kills a wide variety of snails, cestodes and Cercariae by affecting the respiration and the carbohydrate metabolism. It probably disturbs oxidation processes by inhibiting oxygen uptake. The main target pest in agricultural use is the golden apple snail (Pomacea canaliculata) in paddy fields (rice-cultivation) but it is also applied in public health and hygiene programs to control/eradicate snails such as Biomphalaria glabrata, which are intermediate hosts for Schistosoma spp., the infectious agents of schistosomiasis in open waters in tropical Africa. The pesticide is quickly metabolized in water and does not exhibit a long-term effect.

It is also applied to commercially managed fish ponds, in order to clean them from undesirable fish prior to re-filling the pond. Niclosamide is highly toxic to fish but, due to its short half-life in water, the batch of new fish may be added only a few days after application of the pesticide.