2013年10月11日星期五

Is L(-)-Carnitine a medicine to lose weight?

Maybe you have heard something about that L(-)-Carnitine is a useful kind of medicine to Lose weight on the TV advertisement.Is it right or not? Can it really help you to lose weight by only eating it? Next let’s see some information of it.
L(-)-Carnitine,541-15-1


L(-)-Carnitine is a natural substance found in food; however, it is not considered an essential nutrient because the body can make it from the amino acids lysine and methionine. L(-)-Carnitine is the nutrient that transports fatty acids to the mitochondria for use as a fuel source, and research shows that muscle L(-)-Carnitine levels are rapidly depleted during exercise, even moderate exercise.

A number of published studies on athletes have shown that L(-)-Carnitine supplementation supports exercise performance. Athletes have a requirement for more L(-)-Carnitine than they are capable of producing endogenously (inside the body). L(-)-Carnitine may be particularly important during periods of intense exercise as it may help to reduce post-exercise lactic acid accumulation and may increase maximal work output. It may also preserve muscle glycogen levels during exercise.

As reported in the majority of studies, an increase in maximal oxygen consumption and a lowering of the respiratory quotient indicate that dietary L(-)-Carnitine has the potential to stimulate lipid metabolism (e.g. the utilization of fatty acids for fuel). Treatment with L(-)-Carnitine has also been shown to induce a significant post-exercise decrease in plasma lactate, which is formed and used continuously under fully aerobic conditions. Data from preliminary studies have indicated that L(-)-Carnitine supplementation can attenuate the deleterious effects of hypoxic (low oxygen) training and speed up recovery from exercise stress. Recent data have indicated that L(-)-Carnitine plays a decisive role in the prevention of cellular damage and favorably affects recovery from exercise stress.

L(-)-Carnitine is a kind of vitamin B , and its structure is like amino acids, so it was classified as amino acids. Its main role is to help the transport of long-chain fatty acids to support energy. It will prevents fat accumulation in the heart, liver and skeletal muscle . It can prevent diabetes , fatty liver and heart disease in fat metabolism . Taking L(-)-Carnitine can reduce damage to the heart . It can lower blood triglycerides , weight loss also has a role. L(-)-Carnitine to increase vitamin E and vitamin C, antioxidant effect.

L(-)-Carnitine deficiency have congenital, hereditary L(-)-Carnitine synthesis as bad . Symptoms of heartburn, muscle atrophy and obesity. More men than women need L(-)-Carnitine. Vegetarians prone to L(-)-Carnitine deficiency.
If the body has sufficient iron, thiamin, vitamin B6, lysine , methionine and vitamin C, not a lack of L(-)-Carnitine . Carnitine -rich foods are meat and offal.

Synthetic L(-)-Carnitine L-body , dextral body and racemic three forms , with L(-)-Carnitine is better.

L(-)-Carnitine is a function of a variety of physiologically active compounds , and its main function is to promote fatty acid β- oxidation ; also regulate mitochondrial acyl ratios affect energy metabolism ; L(-)-Carnitine branched-chain amino acids may participate in the transport of metabolites , so as to promote the normal metabolism of branched -chain amino acids . In addition, L(-)-Carnitine in the elimination and utilization of ketone bodies play a role , can be used as biological antioxidants scavenge free radicals , maintain membrane stability, improve the animal 's immune system as well as the ability of anti-stress resistance .

Recent studies show that L(-)-Carnitine and acetyl- L(-)-Carnitine on sperm mitochondrial energy metabolism plays an important role in the carrier , can remove ROS, protecting the sperm membrane function . Oral L(-)-Carnitine and acetyl- L(-)-Carnitine on small, weak sperm patients, can improve sperm forward movement total motile sperm count and improve clinical pregnancy the woman , and the safe and effective. Domestic and international clinical studies show that L(-)-Carnitine therapy Nanzaibuyu is a recent breakthrough in the field of drug treatment Nanzaibuyu its in-depth study is necessary, in order to further elucidate its mechanism of action , clarify its indications.

L(-)-Carnitine can be used with organic acids, fatty acid metabolism in vivo sick sick children to generate a large number of acyl-CoA derivatives combined into a water-soluble acyl L(-)-Carnitine from the urine will not only help to control acute episodes of acidosis , can also be effective improve the long-term prognosis .


L(-)-Carnitine is not a weight loss drug , its main role is to burn fat and lose weight not the same thing . In order to use L(-)-Carnitine weight loss , in addition to his burning fat , a lot of exercise to lose weight is still the key , L(-)-Carnitine only play a supporting role . If exercise is not large, such as just dieting , taking L(-)-Carnitine had no effect on weight loss.

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