2013年10月10日星期四

1A,25-dihydroxycholecalciferol



1.Basic information

Product Name: 1alpha,25-Dihydroxycholecalciferol
Synonyms: Vitamin D3, 1a,25-Dihydroxy-; 1alpha,25-Dihydroxyvitamin D3; 1a,25-Dihydroxyvitamin; 1alpha,25-dihydroxycholecalciferol; (5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-dihydroxycholecalciferol; Calcitriol; 1,25-dihydroxyvitamin D3
CAS: 32222-06-3 MF: C27H44O3
MW: 416.64
EINECS: 250-963-8
Product Categories: Miscellaneous Biochemicals;Vitamin D3 analogs;API;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 32222-06-3.mol
mp:  119-1210C
storage temp:  2-8°C
Stability: Air and Light Sensitive

2.Safety Information

Hazard Codes:  T ,Xn
Risk Statements : 26/27/28-63-36/37/38-20/21/22
Safety Statements:  36/37/39-45-36-26
RIDADR:  UN 2811 6.1/PG
WGK Germany : 3
RTECS:  FZ4645000
F:  8-10-19
HazardClass:  6.1(a)
PackingGroup : I
HS Code:  29061900
Hazardous Substances Data: 32222-06-3

3.Biologically information

Chemical Properties: White Crystalline Powder
Usage :The biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic
Biological Activity: Active metabolite of vitamin D 3 that activates the vitamin D receptor (VDR). Displays calcemic actions; stimulates intestinal and renal Ca 2  absorption and regulates bone Ca 2  turnover. Exhibits antitumor activity; inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.

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