Metformin hydrochloride Properties

Metformin hydrochloride is one kind of crystalline solid or white powder. The IUPAC Name of this chemical is 3-(Diaminomethylidene)-1,1-dimethylguanidine hydrochloride. Besides, Metformin hydrochloride belongs to Intermediates & Fine Chemicals; Pharmaceuticals; API's; Miscellaneous Compounds. In addition, Metformin hydrochloride Classification Code is Antidiabetic; Drug / Therapeutic Agent; Skin / Eye Irritant. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether and chloroform.

1. Properties of Metformin hydrochloride

Name:Metformin hydrochloride

EINECS:214-230-6

Molecular Formula:C4H12ClN5

CAS Registry Number:1115-70-4

Appearance:crystalline solid

Molecular Weight:165.62

Boiling Point:224.1 °C at 760 mmHg

Melting Point:223-226℃

Flash Point:89.3 °C

Solubility:Soluble in water, 95% alcohol. Practically insoluble in ether, chloroform.

Biological Activity:Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines.

Usage:An oral hypoglycemic agent

2. Safety information of Metformin hydrochloride
Hazard Codes: Xn

Risk Statements: 22-36/38

R22:Harmful if swallowed.

R36/38:Irritating to eyes and skin.

Safety Statements: 26-36

S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

S36:Wear suitable protective clothing.

WGK Germany: 3

RTECS: DU1800000

3. Uses of Metformin hydrochloride

Metformin hydrochloride is an oral hypoglycemic agent. It can lower plasma glucose levels and improves insulin sensitivity. Metformin hydrochloride Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines.


4. Production of Metformin hydrochloride

Metformin hydrochloride is derived by Dimethylamine salt reacting with Dicyandiamide.