2013年11月9日星期六

Compounds: Folic acid

Folic acid (also known as folate, vitamin M, vitamin B9, vitamin Bc (or folacin), pteroyl-L-glutamic acid, and pteroyl-L-glutamate) are forms of the water-soluble vitamin B9. Folate is composed of the aromatic pteridine ring linked to para-aminobenzoic acid and one or more glutamate residues. Folic acid is itself not biologically active, but its biological importance is due to tetrahydrofolate and other derivatives after its conversion to dihydrofolic acid in the liver.
      
Name:Folic acid

EINECS:200-419-0

Molecular Formula:C19H19N7O6

CAS Registry Number:59-30-3

Appearance:Yellow to orange yellow crystals or crystalline powder

Molecular Weight:441.4

Density:1.68 g/cm3

Melting Point:250℃

Alpha:20 o (C=1, 0.1N NAOH)

Storage Temperature:2-8°C

Solubility:Water Solubility, 1.6 mg/L (25 oC)

Stability:Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.

Usage:Medication.

Chemical Properties: orange to yellow crystalline powder

Usage :A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.

General Description :Odorless orange-yellow needles or platelets. Darkens and chars from approximately 482°F.

Air & Water Reactions: Insoluble in water. Aqueous solutions have pHs of 4.0-4.8.


Reactivity Profile: Acid solutions of Folic acid are sensitive to heat, but towards neutrality, stability progressively increases. Solutions are inactivated
by ultraviolet light and alkaline solutions are sensitive to oxidation. Folic acid is also inactivated by light. Folic acid is incompatible with oxidizing agents, reducing agents and heavy metal ions.


Fire Hazard: Flash point data for Folic acid are not available; however, Folic acid is probably combustible.

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