Bicalutamide chemical properties

Bicalutamide is in a class of medications called nonsteroidal antiandrogens. Bicalutamide is used with another medication to treat metastatic prostate cancer .  It works by blocking the effect of androgen (a male hormone), to stop the growth and spread of cancer cells.

Name:Bicalutamide

Molecular Formula:C18H14F4N2O4S

CAS Registry Number:90357-06-5

Appearance:off-white crystalline solid

Molecular Weight:430.373373

Density:1.52 g/cm3

Boiling Point:650.3 °C at 760 mmHg

Melting Point:191-193°C

Flash Point:347.1 °C

Storage Temperature:Store in original container in a cool dark place.

Refractive index:1.577

Solubility:Insoluble in water

Chemical Properties: Off-White Crystalline Solid

Biological Activity:Orally active non-steroidal androgen receptor antagonist (IC 50 = 190 nM). Displays peripheral selectivity and does not effect serum levels of LH and testosterone. Exhibits potent anticancer activity in vivo .

Usage:Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal)


Side effect:Flushing and sweating (hot flashes), body aches and pains, breast swelling/tenderness/pain, headache, dizziness, drowsiness, trouble sleeping, weakness, hair loss, weight changes, constipation, diarrhea, stomach upset, gas, nausea, vomiting, and loss of appetite may occur.