Where can you get Di-tert butyl dicarbonate?

Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. This carbonate ester reacts with amines to give N-tert-butoxycarbonyl or so-called t-BOC derivatives. These derivatives do not behave as amines, which allows certain subsequent transformations to occur that would have otherwise affected the amine functional group. The t-BOC can later be removed from the amine using acids. Thus, t-BOC serves as a protective group, for instance in solid phase peptide synthesis. It is unreactive to most bases and nucleophiles, allowing for an orthogonal Fmoc protection.
Di-tert-butyl-dicarbonate Using:

1、Di-tert-butyl-dicarbonate (DIBOC) is used  in the organic synthesis to introduce amino acid protection gene.
                               
2、Because it must synthesize one kind of compound similar to the natural multi-peptide, also must connect each kind of optical rotation amino acid to certain length the peptide chain according to certain order, when needed to combine  one kind of amino acid the carboxyl group and another kind of amino acid amino, must prevent to combine identical kind of amino acid mutually, therefore, in synthesis , it must protect certain aminos or the carboxyl group,In order to react in the way which is required to carry on.

3、Di-tert-butyl dicarbonate is one well capable protecting agent for amino acid , utilized specially in the amino acid amino protection, widely applied in the medicine, the protein and the multi-peptide synthesis, biochemistry food, the cosmetics and many kinds of product synthesis.In. Compared with the traditional amino acid protecting agent like chloro-carbonic acid animal pen ester, the chloro-carbonic acid - P wu formic acid, it has the following merit:

a、Competitive price


b、No intense irritant flavor, no harm to human body, but may cause skin allergy if contact the skin directly, and may strip with water.


c、Using this product to synthesize the multi-peptides, the remove condition of this protection gene is temperate, and it is easier to separate the responded product compared with using other types of amino acid protecting agent.


d、Has the ignitability, but does not belong to flammable explosive
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