2013年12月13日星期五

Identification of Rifampicin

Rifampicin or rifampin  is a bactericidal antibiotic drug of the rifamycin group.

1. Properties
Rifampicin C43H58N4O12 (cas 13292-46-1) Molecular Structure

Name:Rifampicin

EINECS:236-312-0

Molecular Formula:C43H58N4O12

CAS Registry Number:13292-46-1

Appearance:Red to orange crystalline solid

Molecular Weight:822.95

Density:1.34 g/cm3

Boiling Point:1004.42 °C at 760 mmHg

Melting Point:183°C (dec.)

Flash Point:561.253 °C

Storage Temperature:2-8°C

Refractive index:1.613

Solubility:slightly soluble

Stability:Stable under normal shipping and handling conditions.

Usage:Semisynthetic antibiotic. Antibacerial (tuberculostatic)

2. Safety Information

Hazard Codes:Xn,Xi

Risk Statements:22-36/37/38-36/38

Safety Statements:26-36-37/39

WGK Germany :3

RTECS:VJ7000000

F :8-10-21

HS Code:29419000

3. Personal protective equipment

1)Eye/face protection

Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

2)Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands

3)Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.


4)Respiratory protection

For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

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