1,2,3-Propanetriol Health Information

1,2,3-Propanetriol is a naturally occurring chemical. 1,2,3-Propanetriol (or glycerine, glycerin) is a simple polyol (sugar alcohol) compound. It is a colorless, odorless, viscous liquid that is widely used in pharmaceutical formulations. 1,2,3-Propanetriol has three hydroxyl groups that are responsible for its solubility in water and its hygroscopic nature. The 1,2,3-Propanetriol backbone is central to all lipids known as triglycerides. 1,2,3-Propanetriol is sweet-tasting and of low toxicity.

1. Personal Protective Equipment

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face

Skin: Wear appropriate protective gloves to prevent skin exposure.

Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators:Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

2. Accidental Release Measures

General Information: Use proper personal protective equipment .

Spills/Leaks:Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation.

3. Handling and Storage

Handling:Wash thoroughly after handling. Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.

Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

4. Potential Health Effects

Eye: May cause eye irritation.

Skin: May cause skin irritation. Low hazard for usual industrial handling.

Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Low hazard for usual industrial handling. May cause headache.

Inhalation: Low hazard for usual industrial handling. Inhalation of a mist of this material may cause respiratory tract irritation.
Chronic: No information found.

5. First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Ingestion: Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur.


6 . Fire Fighting Measures

General Information:As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.

Media:Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.