Voriconazole (vor-i-kon-a-zole, brand name VFEND, Pfizer) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. These are generally seen in patients who are immunocompromised, and include invasive candidiasis, invasive aspergillosis, and certain emerging fungal infections.
Voriconazole is a medicine which is used in certain types of fungal infections.
1. Primary treatment of pulmonary aspergillus
2. Primary treatment of amphotericin B and fluconazole resistant fungal infections (including Fusarium spp. and Scedosporium apiospermum - asexual form of Pseudoallescheria boydii )
3. Treatment of invasive fungal infections in patients who are intolerant of, or refractory to, other antifungal therapy
4. Empirical therapy of neutropenic fever in patients receiving concomitant nephrotoxins (cyclosporin, tacrolimus).
5. Prophylaxis in high risk patients undergoing mini MUD transplants, mini allogeneic BMTs, allogeneic BMTs, or patients with severe graft versus host disease (GVHD).
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