The side effect of Aminophylline

Aminophylline,317-34-0

　　Aminophylline is a mixture of theophylline and ethylenediamine, , acting as a respiratory stimulant, smooth muscle relaxant, myocardial stimulant, and diuretic. It is used as a broncho dilator and also as an antidote to dipyridamole toxicity. Administration may be oral, intramuscular, intravenous, or rectal. If intravenous administration is too rapid it can cause circulatory collapse. Intramuscular administration should be done with caution because aminophylline is very irritating to the tissues. Oral administration must also be cautious because there could be gastric or urinary irritation.
　　SIDE EFFECTS:Stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking (tremors), flushing, and increased urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
　　Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
　　Tell your doctor immediately if any of these unlikely but serious side effects occur: confusion, dizziness, mental/mood changes, muscle twitching/pain/tenderness, weakness, rapid breathing.
　　Tell your doctor immediately if any of these rare but very serious side effects occur:fainting, fast/slow/irregular heartbeat, dark/tarry stools, vomit that looks like coffee grounds, seizures.
　　A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, red/scaly skin, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathin
　　PRECAUTIONS: Before using aminophylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine, caffeine, or ethylenediamine; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain breathing disorder (cystic fibrosis), a certain eye problem (glaucoma), diabetes, heart problems (e.g., congestive heart failure, irregular heartbeat), high blood pressure, current fever/flu-like symptoms, kidney disease, liver disease (e.g., cirrhosis), seizures, stomach/intestinal ulcer, thyroid disease.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Before having surgery, tell your doctor or dentist that you are taking this medication.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects. Careful monitoring of side effects and drug blood levels is recommended.Caution is advised when using this drug in children, especially newborns and children younger than 1 year, because they may be more sensitive to its effects. Careful monitoring of side effects, drug blood levels, and dose adjustment is recommended.Duringpregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Changes in your body during the last 3 months of pregnancy may affect the amount of this drug in your blood. Your doctor should carefully monitor the amount of drug in your blood, as well as any side effects, so that your dose may be changed if needed.This drug passes into breast milk and may have undesirable effects on a nursing infant (e.g., irritability). Consult your doctor before breast-feeding.