Information about Capsaicin

404-86-4

Name:capsaicin
EINECS:206-969-8
Molecular Formula:C18H27NO3
CAS Registry Number:404-86-4
Synonyms:Capsaicine; 8-Methyl-N-vanillyl-6-nonenamide
InChI:InChI=1/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
Appearance:white crystalline powder
Molecular Weight:305.42
Density:1.041g/cm3
Boiling Point:511.5oCat760mmHg
Melting Point:62-65℃
Flash Point:263.1oC
Storage Temperature:2-8°C
Solubility:practically insoluble in cold water
Biological Activity:Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset? .
Stability:Stable. Incompatible with strong oxidizing agents.
Usage:A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.