Information about Cytarabine

EINECS:205-705-9

Molecular Formula:C9H13N3O5

CAS Registry Number:147-94-4

Appearance:fine off-white crystalline powder

Molecular Weight:243.21662

Density:1.89 g/cm3

Boiling Point:545.7°C at 760 mmHg

Melting Point:212 - 213 C

Flash Point:283.8°C

Storage Temperature:2-8°C

Refractive index:1.756

Solubility:Soluble

Stability:Stable.

Usage:

　　1.Cytarabine is mainly used in the treatment of acute myeloid leukaemia, acute lymphocytic leukaemia (ALL) and in lymphomas,where it is the backbone of induction chemotherapy.

　　2.Cytarabine also possesses antiviral activity, and it has been used for the treatment of generalised herpesvirus infection. However, cytarabine is not very selective in this setting and causes bone marrow suppression and other severe side effects, so it is used mainly for the chemotherapy of hematologic cancers.

　　3.Cytarabine is also used in the study of the nervous system to control the proliferation of glial cells in cultures, the amount of glial cells having an important impact on neurons.