Atorvastatin is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in livertissue that plays a key role in production of cholesterol in the body.
1. How to take atorvastain tablets?
Take atorvastatin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Do not break an atorvastatin tablet unless your doctor has told you.
Atorvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day. Your doctor may occasionally change your dose to make sure you get the best results.
To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.
Atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. You may need to take atorvastatin on a long-term basis for the treatment of high cholesterol. Store at room temperature away from moisture, heat, and light.
2.If you take more Atorvastatin Tablets than you should
If you accidently take too many Atorvastatin Tablets (more than your usual daily dose) then contact your doctor or nearest hospital for advice.
3.If you forget to take Atorvastatin Tablets
If you forget to take a dose, just take your next scheduled dose at the correct time.
Do not take a double dose to make up for a forgotten dose.
4.If you stop taking Atorvastatin Tablets
If you have any further questions on the use of this medicine or wish to stop your treatment, ask your doctor or pharmacist.
5.What special dietary instructions should I follow?
Eat a low-fat, low-cholesterol diet.Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian.Avoid drinking large amounts [more than 1.2 liter (approximately 1 quart) per day] of grapefruit juice while taking atorvastatin.
6. Possible side effects
As stated earlier, myopathy with elevation of creatinine kinase (CK) and rhabdomyolysis are the most serious side effects, although rare at <1%. Headache is the most common side effect, occurring in more than 10% of patients. Side effects that occur in 1–10% of patients taking atorvastatin include:
*Weakness
*Insomnia and dizziness
*Chest pain and peripheral edema
*Rash
*Abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea
*Urinary tract infection
*Arthralgia, myalgia, back pain, arthritis
*Sinusitis, pharyngitis, bronchitis, rhinitis
*Infection, flu-like syndrome, allergic reaction
Atorvastatin and other statins are associated with anecdotal reports of memory loss by consumers, which have been seen in clinical practice in a tiny percentage of users, particularly women. Evidence is conflicting with anecdotal reports contrasting with a well-established association of high cholesterol with dementia. However, it is known that cholesterol synthesis is necessary for normal neuron functioning. According to Pfizer, the manufacturer of Lipitor, clinical trials "do not establish a causal link between Lipitor and memory loss."
Elevation of alanine transaminase (ALT) and aspartate transaminase (AST) has been described in a few cases.
High-dose
atorvastatin had also been associated with worsening glycemic control.
7.How to store atorvastain tablets
Keep out of the reach and sight of children.
Store in the original package in order to protect from moisture. This medicine does not require any special temperature storage conditions.
Do not use Atorvastatin Tablets after the expiry date which is stated on the carton label and blister foil after Exp. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
8.Other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests during your treatment , especially if you develop symptoms of liver damage.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking atorvastatin.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
