2014年2月25日星期二

Chemical Properties of L-Valine

L-Valine, with the IUPAC Name of (2S)-2-amino-3-methylbutanoic acid, is one kind of white crystalline powder. This belongs to the Product Categories which include Amino Acids;Amino Acid Derivatives;Valine ;Amino Acids and Derivatives;alpha-Amino Acids;Biochemistry;Nutritional Supplements;Amino Acids.

L-Valine, or valine, is a proteinogenic amino acid that the body uses in the synthesis of protein. It is one of the branched chain amino acids (BCAAs) responsible for repairing and strengthening the muscle tissues. Being an essential amino acid, it must be obtained from the diet or through supplements. This amino acid can be obtained from a variety of foods, including both animal and plant foods.

1. Uses

There are many benefits of L-Valine for those who engage in regular exercise and bodybuilding. When present, it helps to increase the strength and endurance of the muscles and speeds up the recovery of fatigued muscles after workouts or competitions. A speedy recovery of the muscles can prevent them from breaking down and losing their tone. As a result of those benefits, L-Valine supplements are often taken by bodybuilders and competing athletes to maintain and improve their strength.

Other benefits include a reduced appetite, which can help to maintain a healthy weight. The metabolism of glucose, a form of sugar that the body uses for energy, is also improved. Those who have trouble sleeping can benefit due to its ability to reduce insomnia. It can also reduce nervousness and strengthen the immune system. A strong immune system in return is able to prevent a host of serious illnesses and common ailments.

2. Properties of L-Valine

Name:L-Valine
EINECS:200-773-6
Molecular Formula:C5H11NO2
CAS Registry Number:72-18-4 
InChI:InChI=1/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
HS Code:29224995
Appearance:White crystalline powder
Molecular Weight:117.15
Density:1.23
Boiling Point:213.6 °C at 760 mmHg
Melting Point:315 °C
Flash Point:83 °C
Alpha:28 o (C=8, 6N HCL)
Storage Temperature:Store at RT
Refractive index:1.507
Solubility:85 g/L (20 °C)

3. Structure Descriptors of L-Valine

You could convert the following datas into the molecular structure:
(1)Canonical SMILES: CC(C)C(C(=O)O)N
(2)Isomeric SMILES: CC(C)[C@@H](C(=O)O)N
(3)InChI: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
(4)InChIKey: KZSNJWFQEVHDMF-BYPYZUCNSA-N

4. Safety Information of L-Valine

Hazard Codes: Xn
Risk Statements: 40
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 24/25-36-22
S24/25:Avoid contact with skin and eyes.
S36:Wear suitable protective clothing.
S22:Do not breathe dust.
WGK Germany: 3
RTECS: YV9361000
HS Code: 29224995
Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

5. Production of L-Valine

Racemic valine can be synthesized by bromination of isovaleric acid followed by amination of the α-bromo derivative
HO2CCH2CH(CH3)2 + Br2 → HO2CCHBrCH(CH3)2 + HBr
HO2CCHBrCH(CH3)2 + 2 NH3 → HO2CCH(NH2)CH(CH3)2 + NH4Br

没有评论:

发表评论